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May 11th, 2018 by Abraham

The monotherapy arms analysis maa long-term update of the efficacy of femara monotherapy compared to tamoxifen monotherapy median duration of adjuvant treatment 5 years is presented in table 5.

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tamoxifen is metabolized by cyp3a4 and cyp2d6, and to a smaller extent by cyp2c9 and cyp2c19, to other potent, active metabolites including endoxifen, which have up to 33 times more affinity for the estrogen receptor than tamoxifen.

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the benefit of tamoxifen increases with the duration of treatment; the proportional reductions in 10-year recurrence and mortality were 47 and 26 , respectively, with 5-year regimens of tamoxifen therapy.

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64 furthermore, tamoxifen treatment alone has been shown to have anti-angiogenetic effects in animal models of cancer which appear to be, at least in part, independent of tamoxifen s er antagonist properties.

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anne, i did notice that you said you have finished taking the tamoxifen after 5 years, why would you need to take evista.


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